Pathogen-host interactions
Understanding what happens during infection from both the host and the pathogen perspective is essential for the development of novel therapeutics. The laboratory uses cutting-edge technology such as RNA sequencing to determine the transcriptome of both host and pathogen during infection. This data is then used to identify novel targets for the development of immunotherapies.
Immunotherapies
Antibiotics have revolutionized modern medicine. Their extensive use and bacterial adaptation however have led to record levels of antimicrobial resistance, which makes the treatment of these infections often difficult.
The laboratory investigates alternatives such as vaccination as a prevention method, or the use of monoclonal antibodies to help the immune system fight infections.
Molecular tools
Antibiotics have revolutionized modern medicine. Their extensive use and bacterial adaptation however have led to record levels of antimicrobial resistance, which makes the treatment of these infections often difficult.
The laboratory investigates alternatives such as vaccination as a prevention method, or the use of monoclonal antibodies to help the immune system fight infections.